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No. 007 · GH & Growth · Recovery Peptide

PEG-MGF

PEGylated MGFPEG-MGFMechano growth factor

C Tier C · Animal data how tiers work →
  • Not FDA approved
  • WADA ✗ S2
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Fingerprint no sequence
PEG-MGF (no defined sequence)

No sequence on file. We only draw fingerprints from published sequences — this ring motif is a placeholder, never a guessed sequence.

01

Evidence

  1. D In vitro
  2. C Animal
  3. B Human pilot
  4. A RCT
  5. S Approved

TIER C — Evidence comes mostly from animal studies.

Only cell and animal studies are published; no human trials.

Tiers rate the strength of published evidence — not effectiveness, safety, or a recommendation.

02

At a glance

Routes studied
Intramuscular, Subcutaneous Routes used in published research
FDA
Not approved
WADA
Prohibited · S2 Peptide hormones, growth factors, related substances and mimetics
03

Overview

A PEGylated form of mechano-growth factor that extends its half-life, promoting muscle repair and satellite cell activation following exercise-induced damage.

Research status Limited human data; preclinical research supports role in muscle repair signaling

04

Mechanism

PEG-MGF is a PEGylated splice variant of IGF-1 (the Ec isoform) produced by mechanically stressed muscle tissue. It activates satellite cells and promotes their proliferation without triggering differentiation, thereby expanding the pool of muscle precursor cells available for repair. PEGylation extends its half-life from minutes to hours.

05

Effects reported in research

Reported outcomes, not promises. These come mostly from preclinical (cell or animal) research and have not been confirmed in human trials.

  • Accelerated muscle recovery post-exercise
  • Satellite cell proliferation
  • Localized muscle tissue repair
  • Reduced delayed-onset muscle soreness
06

Safety & unknowns

Very limited human safety data. Preclinical studies suggest localized injection site reactions. Theoretical risk of uncontrolled cell proliferation. Not FDA-approved. Banned by WADA.

Unknowns. No randomized controlled trials in humans have been published, so human safety has not been established in controlled studies.

Informational only — not medical advice. peptidemeta publishes no dosing, protocols, or sourcing. Talk to a qualified clinician about any treatment decision.

07

Studies [0]

No studies cited for this entry yet.

09

Status sources

Sources behind the tier, regulatory status, sequence and dates on this page.

10

Cite this entry

$ cite --format=apa

peptidemeta. (2026). PEG-MGF. In peptidemeta: The peptide library, ranked by evidence. Retrieved November 8, 2026, from https://peptidemeta.com/p/peg-mgf/

$ cite --format=bibtex 
@misc{peptidemeta-peg-mgf,
  title = {PEG-MGF},
  author = {{peptidemeta}},
  year = {2026},
  howpublished = {\url{https://peptidemeta.com/p/peg-mgf/}},
  note = {Accessed 2026-11-08}
}

Accessed date reflects when you opened this page. Cite primary studies for scientific claims.

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